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Epigenetics: Unwrapping the Future for Drug Discovery?

Thursday, October 20, 2011

Bentley University
Waltham, Massachusetts

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Program

8:00-9:00

Check-in, Light breakfast, / Exhibitor setup

9:00-9:10

Opening Remarks
Rajvi Chopra, Novartis

Session I 

Chair: Sharon Townson

9:10-9:55

"Defining the Cancer Epigenome and its Potential for Therapeutic Targeting"
Stephen Baylin, The John Hopkins University - School of Medicine

9:55-10:30

"Protein Methyltransferase Inhibitors as Personalized Cancer Therapeutics"
Robert Copeland, Epizyme

10:30-11:00

Coffee

Session II 

Chair: Nessa Carey

11:00-11:35

"The Intersection of Structural Biology and Epigenetics"
Steve Bellon, Constellation Pharmaceuticals

11:35-12:20

"Structural and chemical biology of readers and writers of the histone code"
Cheryl Arrowsmith, SGC - Toronto

12:20-1:10

Lunch

Session III

Chair: Elizabeth Sprague

1:10-1:55

"Mechanisms for Coordinated DNA Methylation and Histone Methylation"
Xiaodong Cheng, Emory University School of Medicine

1:55-2:30

"Chemical Inhibition of Bromodomains"
James Bradner, Dana Farber Cancer Institute / HMS

2:30-3:00

Coffee

Session IV

Chair: Steven Kazmirski

3:00-3:35

"Molecular recognition of nucleosomes by chromatin factors and enzymes"
Song Tan, Penn State University

3:35-4:10

"Structural Basis of Substrate Methylation and Inhibition of SMYD2"
Andrew Ferguson, AstraZeneca

4:10-4:45

"Epigenetic therapies in non-oncology indications - the opportunities and the challenges"
Nessa Carey, Pfizer UK

4:45

Mixer

Organizing Committee

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Meeting Sponsors

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