Infectious Disease and Drug Discovery

June 20, 2008

Bentley College, Waltham, MA

Tentative Agenda
(Subject to change)

8:00 - 9:00 

Check-in and breakfast

9:00 - 10:00 

Antibacterial Drug Discovery in the 21st Century: Is There Any Hope?

Steve Projan, Wyeth Research, Cambridge, MA
10:00 -10:30

Structure Guided Target Evaluation for Antibacterial Drug Discovery

Sushmita Lahiri, AstraZeneca Pharmaceuticals, Waltham, MA
10:30 - 11:00  Break
11:00 - 11:30 

Riboswitches

Ken Blount
11:30 -12:00 

Ribosome talk, TBA

Rib-X Pharmaceuticals, TBA
12:00 - 1:00  Lunch
1:00 - 2:00 

Structural Biology and an Effective HIV-1 Vaccine

Peter Kwong, Vaccine Research Center, NIH, Bethesda, MD
2:00 - 3:00 

Reducing Risk in Drug Discovery, Preclinical Development of the Hepatitis C Virus Protease Inhibitor Telaprevir (VX-950)

Ann Kwong, Vertex Pharmaceuticals, Cambridge, MA
3:00 - 3:30  Break
3:30 - 4:00

Biophysical Approaches to Target-Based Discovery of Novel Antibacterials

Gunther Kern, AstraZeneca Pharmaceuticals, Waltham, MA
4:00 - 5:00 

Mining the Magic Mountain for Novel Inhibitors of Menaquinone and Fatty Acid Biosynthesis in Mycobacterium Tuberculosis: Slow Onset Inhibition and In Vivo Activity

Peter Tonge, Institute for Chemical Biology and Drug Discovery, SUNY Stony Brook, NY
5:00 - 7:00  Mixer

Registration is now open


Mission statement:

The New England Structural Biology Association (NESBA) is a non-profit organization, run by volunteers. We are dedicated to bringing together industrial scientists with the shared vision of using protein structure to enable the design of novel therapeutics. 

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