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Epigenetics: Unwrapping the Future for Drug
Discovery?
Thursday, October 20, 2011
Bentley
University
Waltham, Massachusetts
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Program
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8:00-9:00
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Check-in, Light breakfast, / Exhibitor setup |
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9:00-9:10
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Opening Remarks
Rajvi Chopra, Novartis |
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Session I
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Chair: Sharon Townson |
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9:10-9:55
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"Defining the Cancer Epigenome and its Potential for Therapeutic
Targeting"
Stephen Baylin, The John Hopkins University - School of Medicine |
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9:55-10:30
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"Protein Methyltransferase Inhibitors as Personalized Cancer
Therapeutics"
Robert Copeland, Epizyme |
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10:30-11:00
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Coffee |
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Session II
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Chair: Nessa Carey |
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11:00-11:35
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"The Intersection of Structural Biology and Epigenetics"
Steve Bellon, Constellation Pharmaceuticals |
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11:35-12:20
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"Structural and chemical biology of readers and writers of the
histone code"
Cheryl Arrowsmith, SGC - Toronto |
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12:20-1:10
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Lunch |
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Session III
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Chair: Elizabeth Sprague |
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1:10-1:55
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"Mechanisms for Coordinated DNA Methylation and Histone
Methylation"
Xiaodong Cheng, Emory University School of Medicine |
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1:55-2:30
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"Chemical Inhibition of Bromodomains"
James Bradner, Dana Farber Cancer Institute / HMS |
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2:30-3:00
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Coffee |
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Session IV
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Chair: Steven Kazmirski |
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3:00-3:35
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"Molecular recognition of nucleosomes by chromatin factors and
enzymes"
Song Tan, Penn State University |
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3:35-4:10
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"Structural Basis of Substrate Methylation and Inhibition of
SMYD2"
Andrew Ferguson, AstraZeneca |
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4:10-4:45
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"Epigenetic therapies in non-oncology indications - the
opportunities and the challenges"
Nessa Carey, Pfizer UK |
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4:45
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Mixer |
Organizing Committee
Check back for more information
Meeting Sponsors
Registration is now closed
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