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2nd Annual New England Protein Science Forum

New Techniques in Protein Sciences - developments in protein science for biopharma and drug discovery

Bentley College, Waltham
Friday, November 7, 2008

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Agenda

8:00 am 

Check-in and light breakfast

9:00—9:10

Introduction
Rajiv Chopra, NESBA

Session I—Overcoming Challenges in Protein Expression & Purification
(Session chair: Ian Hunt)

9:10—9:45

Overcoming the challenges in supplying proteins for drug discovery; tricks and lessons learned in producing difficult to express proteins
Xin Huang, Amgen, Cambridge, MA

9:45—10:20

E.coli and Baculovirus generated proteins for structure based drug design
James M. Groarke, Protein Structure Group, Novartis Institute for Biomedical Research, Cambridge, MA

10:20—10:55

PER.C6® a Human Cell Line Expression platform
Blanca Lain, PERCIVIA, LLC, Cambridge, MA

10:55—11:10

Coffee Break and Posters Session

Session II—Advances in protein analytics & expression technologies
(Session chair: Ted Fox)

11:10—11:45

Proteomics—Discovery and Translation of Biomarkers for Early Clinical Development
Cloud Paweletz, Molecular Profiling Proteomics, Merck Research Laboratories, Boston, MA

11:45—12:20

Analytical Untracentrifugation Applied to Drug Discovery and Development
John Doran, Vertex, Cambridge, MA

12:20—1:00

Lunch

Session IIIA—Biologics & Vaccines: Current trends and developments
(Session chair: Simon Low)

1:00—2:00

Keynote Speaker:

Stapled Peptides: A New Therapeutic Modality
Tomi Sawyer, Aileron Therapeutics, Cambridge, MA

2:00—2:35

Adnectins: Novel Targeted Biologics
Jochem Gokemeijer, Adnexus, Waltham, MA

2:35—2:50

Break and Posters Session

Session IIIB—Biologics & Vaccines: Current trends and developments
(Session chair: Stephen Chambers)

2:50—3:25

From Gene to a Marketed Biologic: An Overview of the Process and Points to Consider
Darren Baker, Biogen Idec, Cambridge, MA

3:25—4:00

Production, Biochemical, Biophysical, and Immunological Characterization of Vaccines
Indresh Srivastava, Novartis Vaccines, Cambridge, MA

4:00—4:35

Biological Therapeutics by Design Using Engineered Heterodimeric Fc Domains
Jonathan Davis, Adnexus, Waltham, MA

4:35 onwards

Mixer and Posters Session

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