First Annual Meeting

Systems Biology in Drug Discovery
Thursday October 5, 2006
Bentley College, Waltham, MA

Keynote Speakers
Dr. Peter Sorger, Prof. of Biological Engineering, MIT 
Dr. James Collins, Prof. of Biomedical Engineering, Boston University
and speakers from
Cell Signaling Technology, Broad Institute, Genstruct, 
GE Global Research Center, BG Medicine, Stanford University

Panel discussion: Integrating modeling into drug discovery
with representatives from 
Pfizer, Astra-Zeneca, Sanofi-Aventis, Novartis and Vertex

Final Program

7:30

Registration and light breakfast  

8:15

Opening remarks Brian Hare

8:30

Keynote Speaker: "Harnessing gene networks in drug discovery" Dr. James Collins, Boston University

9:30

"Identification of activated tyrosine kinases in human cancer using PhosphoScan® technology"  Dr. Roberto Polakiewicz, Cell Signaling Technology

10:00

"Gene expression based high throughput screening and its application to cancer"  Dr. Ken Ross, Broad Institute

10:30

"A systems biology approach for understanding of mechanisms of drug-induced vascular injury"  Dr. Keith Elliston, Genstruct

11:00

Break

11:15

Panel discussion: Integrating Modeling into Drug Discovery  Moderator: Carolyn Cho 
  • Dr. David de Graaf, Pfizer
  • Dr. Alan Buckler, Novartis
  • Dr. Mike Briggs, Vertex
  • Dr. Jack Beusmans, AstraZeneca R&D Boston
  • Dr. Jack Pollard, Sanofi-Aventis

12:30

Lunch

1:30

"Integrating modeling into imaging agent development"  Dr. Brion Sarachan, Global Research Center

2:00

"Integrated correlation networks for systems pathology & systems pharmacology"  Dr. Tom Plasterer, BG Medicine

2:30

"Human cell systems biology for chemical genomics and drug discovery: taking advantage of complexity in cellular models of disease"  Dr. Eugene Butcher, Stanford University

3:00

Keynote Speaker: "Systems pharmacology and anti-cancer therapy"  Dr. Peter Sorger, MIT 

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