2006 Inaugural New England Structural Biology Association Meeting

Protein Kinases and Drug Discovery
Friday March 3, 2006
Bentley College, Waltham, MA

Keynote Speakers
Prof. Stephen C. Harrison, Harvard University 
Dr. Sandra Jacobs, Novartis (Basel)
and speakers from: Vertex, Amgen, Wyeth, Pfizer, Novartis, Transform

Final Program

8:00-9:00

An Accelrys Breakfast  

9:00-9:15

Introductory remarks  

9:15-10:15

Keynote Speaker: "Viral fusion proteins as targets for viral entry inhibitors" Professor Stephen C Harrison - Harvard University

10:15-10:45

"Crystal structures of MEK1 and MEK2: Novel mode of kinase inhibition and implications in drug design"  Huifen Chen - Pfizer (Ann Arbor, Michigan)

10:45-11:00

An IBM coffee break  

11:00-11:30

"Classification of kinase X-ray structures reveals discrete conformations with distinct ligand binding pockets"  Brian Hare - Vertex

11:30-12:00

"Crystallography and Drug Discovery of VEGF Receptor Kinase Inhibitors."  Doug Whittington - Amgen

12:00-1:00

A Rigaku Lunch - "Improving your Pipeline"
Joseph Ferrara - Rigaku (12:30 - 1:00)

1:00-2:00

Keynote Speaker: "What we did to support drug discovery for the Gleevec- follow-up project"  Dr Sandra Jacobs - Novartis (Basel)

2:00-2:30

"The practical challenges of designing Kinase drugs; a modeling perspective"  Ian McFadyen - Transform Pharmaceuticals

2:30-3:00

"The biology of PKCs"  Divya Chaudry - Wyeth

3:00-3:30

A GENEWIZ Coffee break  

3:30-4:00

"Baculovirus expression of protein kinases: Lessons learnt"  Ian Hunt - Novartis

4:00-4:30

"TBD"  Ernst ter Haar - Vertex

5:00-7:00

A Fluidigm Mixer  

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